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Angina kezelés során a diabetes, Magyar Diabetes Társaság On-line

angina kezelés során a diabetes

This is not a simple consequence of atherosclerosis developing more frequently and earlier as well as in a more severe form in diabetes. The decrease in the capacity of oxygen delivery contributes also to this phenomenon as a consequence of enhanced glycation of haemoglobin in the erythrocytes.

Furthermore, the development of microangiopathy in cerebral and coronary vessels may aggravate hypoxia and ischaemia in these organs, and the energy-wasting as well as more oxygen-requiring metabolic processes may develop following the step by step denervation of the heart due to cardiovascular autonomic diabetic neuropathy.

angina kezelés során a diabetes

High doses of benfotiamin could moderate the evolvement of diabetic autonomic neuropathy, and the new piperazidine derivative, trimetazidine provides a fundamentally new method in the cardioprotection.

The direct cardioprotective effect of trimetazidine was demonstrated in angina pectoris, in myocardial infarction as well as during PTCA and open heart surgery.

Kérem várjon! A szív egészsége és a cukorbetegség Szívbetegség és sztrók A szívroham és a sztrók tünetei A szívroham és a sztrók kezelése A szívbetegség és a sztrók megelőzése A szervezet minden részének állandó oxigénellátásra van szüksége ahhoz, hogy jól működjön, különösen igaz ez a szívre és az agyra. Az oxigénben gazdag vér a verőerek artériák kiterjedt hálózatán keresztül áramlik szét a testben.

Our preliminarz observations indicate that the cardioprotective, antianginal effect of trimetazidine could be observed only in diabetic patients with good metabolic control. The Firmingham study. JAMA Brit Med J 3: Diabetes Vaisrub, S: The autonomous heart in diabetic autonomic neuropathy.

angina kezelés során a diabetes

N Engl J Med Ann Int Med Opie, LH: Fuels: Carbohydrates and lipids. Raven Press, New York, Cardiovasc Res Am J Physiol HH, J Nucl Med Raven Press, New York,pp Springer, Budapest, Diabetologia Clin Trials and Meta-Analysis Fantini, E. J Mol Cell Cardiol Lallouette, A: Metabolic agents for diabetic patients with angina pectoris: the use of trimetazidine. Heart and Metabolism 2: Mol Cell Biochem Guarnieri, C, Muscari, Angina kezelés során a diabetes Beneficial effects of trimetazidine on mitochondrial function and superoxide production in the cardiac muscle of monocrotaline-treated rats.

Biochem Pharmacol Cardiovasc Drug Ther 1: Patmore, L, Duncan, GP: Effects of calcium channel antagonists and facilitators on beating of primary cultures of embryonic chick.

angina kezelés során a diabetes

Br J Pharmacol, J Cardiovasc Pharmacol Gaz Med Fr 91 Suppl 26 : Maupoil, V: Direct mesurement of free radical generation in isolated rat heart by electron paramagnetic resonance spectroscopy: effect of trimetazidine.

Adv Exp Biol Med J Cardiovasc Surg Eur Heart J Eu Heart J Eur J Clin Pharmacol Clin Pharmac Am J Cardiol 8BB, Curr Therap Res Michaelides, AP, Spiropoulos, K, Dimopoulos, K, Athanasiades, D, Toutouzas, P: Antianginal efficacy of the combination of trimetazidine-propranolol compared with isosorbide dinitrate-propranolol in patients with stable angina.

Clin Drug Invest Cardiovasc Drugs and Therap 4: Manchanda, SC, Krishnaswami, S: Combination treatment with trimetazidine and diltiazem in stable angina pectoris.

angina kezelés során a diabetes

Heart Cardioscan 3. Suppl A : ,

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